What is Restylane® Refyne and Defyne?

As part of the Restylane® family of products, Restylane® Refyne and Defyne are designed to provide noticeable and natural-looking facial rejuvenation without the need for surgery. Made from a specially-formulated type of hyaluronic acid called XpresHAn® technology, these two innovative products can soften wrinkles around the nose and mouth, particularly smile lines (nasolabial folds) and marionette lines (at the corner of the mouth). Additionally, Refyne can be used to soften fine lines and augment the lips. The difference between the two FDA-approved fillers is the power of correction. Refyne gel is primarily intended to address mild to moderate signs of aging, while Defyne works to smooth and plump deeper creases and folds. Both Restylane® Refyne and Defyne are for patients 21 years of age or older, and the outcome typically lasts about one year, although your experience may vary. Some minor bruising, swelling, and redness is common, though these effects usually subside quickly. We also offer OcuMend® to help minimize side effects.