Restylane® Refyne and Defyne

What is Restylane® Refyne and Defyne?

As part of the Restylane® family of products, Restylane® Refyne and Defyne are designed to provide noticeable and natural-looking facial rejuvenation without the need for surgery. Made from a specially-formulated type of hyaluronic acid called XpresHAn® technology, these two innovative products can soften wrinkles around the nose and mouth, particularly smile lines (nasolabial folds) and marionette lines (at the corner of the mouth). Additionally, Refyne can be used to soften fine lines and augment the lips. The difference between the two FDA-approved fillers is the power of correction. Refyne gel is primarily intended to address mild to moderate signs of aging, while Defyne works to smooth and plump deeper creases and folds. Both Restylane® Refyne and Defyne are for patients 21 years of age or older, and the outcome typically lasts about one year, although your experience may vary. Some minor bruising, swelling, and redness is common, though these effects usually subside quickly. We also offer OcuMend® to help minimize side effects.

What to Expect During Treatment

Dr. Eugenie Brunner, a top facial plastic surgeon, will evaluate your areas of concerns and develop a customized treatment plan. She will then administer the dermal filler into a series of targeted locations to achieve the optimal outcome. Both Restylane® Refyne and Defyne can provide instantaneous results, so you should be able to see the effects right away. Some bruising and tenderness may occur, which is why Dr. Brunner uses the OcuMend® adhesive patch to reduce these symptoms. Once the procedure is complete, typically 15 to 30 minutes after beginning, you can return to your normal schedule.

OcuMend® Healing Gel Patch

To reduce the unwanted effects of dermal filler injections, OcuMend® can be used to minimize and potentially eliminate bruising and redness. Dr. Brunner offers this innovative treatment with all cosmetic injectable treatments to enhance your recovery and outcome.

Would you like to learn more about Restylane® Refyne and Defyne? Talk to our skilled medical team today to schedule a consultation and discuss your goals with Dr. Brunner.

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Lasers & Devices

Happy Patients

Years Experience

Laser Procedures

Facial Plastic Surgeries

Regional & National Awards

We Look Forward to Meeting You!

Double Board Certified: Facial Plastic & Reconstructive Surgery & Otolaryngology Head & Neck Surgery

Castle Connolly Top Doctor for 10 years (2009-2019) in Cosmetic Facial Plastic Surgery

Fellow, American Academy of Facial Plastic & Reconstructive Surgery

Fellow, American College of Surgeons


Most Comprehensive Skin Rejuvenation Laser Center in Central New Jersey

Thousands of Cosmetic Facial Plastic Procedures Performed

Patients' Choice Award for Favorite Physician

Compassionate Doctor

Town Topics Readers' Choice Awards

Eugenie Brunner, MD, FACS

256 Bunn Drive, Suite 4, Princeton, NJ 08540

609.921.9497

5.0 Stars from 22 Reviews

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