While medications like Ozempic® and Wegovy® have revolutionized weight loss, many patients experience an unexpected side effect: rapid facial volume loss, commonly referred to as Ozempic Face. This condition is characterized by hollowed cheeks, sunken temples, pronounced nasolabial folds, and loose, sagging skin that can make you appear older and more tired than you feel.
The good news? Advanced cosmetic treatments can effectively restore facial volume and rejuvenate your appearance while you maintain your weight loss success.
What is Ozempic Face?
Ozempic face refers to the facial aging and volume loss that can occur with rapid weight loss from GLP-1 medications like Ozempic, Wegovy, Mounjaro®, and Zepbound®. When you lose a significant amount of weight quickly, you don’t just lose fat from your body; you also lose fat from your face, which provides structure and youthful contours.
Common signs of Ozempic face include:
- Hollow or sunken cheeks
- Loss of volume in the temples
- Deeper nasolabial folds (smile lines)
- Pronounced marionette lines
- Loose, sagging skin, turkey neck
- A gaunt or aged appearance
- Loss of jawline definition and jowling
Non-Surgical Treatments for Ozempic Face
For most patients experiencing facial volume loss, Dr. Brunner recommends non-surgical or minimally invasive treatments that deliver natural-looking rejuvenation without downtime.
Dermal Fillers
Dermal fillers are one of the most effective solutions for Ozempic face. Injectable fillers like Restylane, Juvéderm®, Sculptra®, and Radiesse fillers strategically restore lost volume, recreating youthful facial contours.
How fillers address Ozempic face:
- Sculptra stimulates your body’s natural collagen production over time, gradually restoring facial volume for results that can last up to two years
- Juvéderm and Restylane fillers provide immediate volume restoration in the cheeks, temples, and midface
- Structural fillers like Radiesse can redefine the jawline and restore fullness to hollow areas
- Softer fillers address fine lines around the mouth and nose
RF Microneedling
RF Microneedling improves skin quality and stimulates collagen production from within. This treatment is particularly effective for addressing:
- Crepey skin texture
- Fine lines and wrinkles
- Mild Skin laxity
- Overall skin rejuvenation
By creating controlled micro-injuries, microneedling triggers your body’s natural healing response, producing fresh collagen and elastin that tighten and firm the skin over time. Multiple sessions typically provide optimal results.
RF Skin Tightening
Radiofrequency (RF) skin tightening uses controlled heat energy to stimulate collagen remodeling deep within the skin layers. This non-invasive treatment effectively addresses:
- Mild to moderate skin laxity
- Jowls and loss of jawline definition
- Sagging skin on the cheeks and neck
- Loose skin texture
RF treatments require minimal downtime, and results continue to improve over several months as new collagen forms. Most patients benefit from a series of treatments for optimal skin tightening.
At our practice, we’re proud to offer Morpheus8 Burst, QuantumRF 10, Fractora, and FaceTite Turbo as quality options to address the symptoms of Ozempic face. Dr. Brunner will determine which device is right for you during your initial consultation.
SmartLipo™-PrecisionTx® with RF Microneedling for Jawline and Neck Contouring
For patients experiencing moderate skin laxity and persistent pockets of fat along the jawline and neck, Dr. Brunner offers SmartLipo-PrecisionTx combined with RF microneedling. This approach bridges the gap between non-invasive treatments and surgical options, making it an effective solution for those who need more than fillers and lasers alone but are not yet candidates for facelift surgery.
How SmartLipo-PrecisionTx with RF microneedling addresses Ozempic face:
- SmartLipo-PrecisionTx uses laser-assisted technology to target stubborn fat deposits beneath the chin and along the jawline
- Controlled thermal energy tightens skin from within
- RF microneedling addresses surface skin quality and texture
- The combination stimulates collagen production for progressive tightening and firming
- Results include a more defined jawline, reduced neck fullness, and improved skin texture
This minimally invasive treatment offers less downtime than traditional surgical procedures while delivering noticeable contouring and tightening results for moderate Ozempic face concerns.
Combination Treatments for Ozempic Face
Dr. Brunner often recommends combining treatments for comprehensive facial rejuvenation. For example:
- Dermal fillers to restore volume + RF skin tightening to address laxity
- Sculptra for gradual volume restoration + RF microneedling for skin quality
- Strategic filler placement + Dysport® or Botox® to smooth wrinkles and fine lines
This customized approach addresses both volume loss and skin quality for the most natural, harmonious results.
Surgical Options for Advanced Cases
For patients with significant facial volume loss and substantial skin laxity, non-surgical treatments may not provide adequate correction. In these cases, Dr. Brunner may recommend a a surgical solution:
Face and Necklift
A surgical face and necklift addresses moderate to severe facial aging by:
- Lifting and repositioning sagging facial tissues
- Removing excess skin
- Tightening underlying muscles
- Restoring jawline definition
- Creating long-lasting, natural-looking rejuvenation
A facelift can be combined with other non-surgical options like RF skin tightening to restore volume while simultaneously tightening loose skin, providing comprehensive correction of Ozempic face.
How a Face and Neck Lift Can Reverse the Effects of Ozempic Face
For patients with significant Ozempic face affecting both the lower face and neck area, Dr. Brunner performs combined face and neck lift procedures that provide comprehensive correction.
This combined surgical approach lifts and repositions facial tissues, removes excess skin, and tightens underlying muscles to refine the jawline and restore definition. For patients who have experienced significant volume loss, Dr. Brunner may incorporate fat grafting to replenish depleted areas and restore youthful fullness while simultaneously addressing skin laxity.
By rejuvenating both the face and neck in one procedure, patients experience a smooth, natural-looking transformation and complete correction of even an extreme Ozempic face with just one recovery period.
How to Prevent Ozempic Face
While not all volume loss can be prevented, Dr. Brunner recommends:
- Losing weight gradually when possible
- Maintaining excellent skin care with retinoids and sunscreen
- Starting facial treatments early in your weight loss journey
- Staying well-hydrated
- Considering proactive filler treatments as you lose weight
Discover How to Fix Ozempic Face with Dr. Brunner
Dr. Eugenie Brunner is a double board-certified facial plastic surgeon who understands the unique concerns of patients experiencing Ozempic face. With her expertise in both surgical and non-surgical facial rejuvenation, she can create a customized treatment plan to restore your facial volume and contours while maintaining natural-looking results.
Whether you’re just beginning to notice volume loss or are dealing with advanced facial aging from rapid weight loss, Dr. Brunner offers comprehensive solutions tailored to your needs and goals.
Schedule a consultation today!
To learn more about Ozempic face, check out this study from the National Institutes of Health (NIH).