Please ensure Javascript is enabled for purposes of website accessibility Restylane Refyne & Defyne | Princeton, NJ | Brunner MD
Dr. Brunner in Princeton, NJ evaluating a patient before dermal fillers

Restylane Refyne and Defyne

What is Restylane Refyne and Defyne?

As part of the Restylane family of products offered at our Princeton medical spa, Restylane Refyne and Defyne are designed to provide noticeable and natural-looking facial rejuvenation without the need for surgery. Made from a specially-formulated type of hyaluronic acid called XpresHAn technology, these two innovative products can soften wrinkles around the nose and mouth, particularly smile lines (nasolabial folds) and marionette lines (at the corner of the mouth). Additionally, Refyne can be used to soften fine lines and augment the lips. The difference between the two FDA-approved fillers is the power of correction. Refyne gel is primarily intended to address mild to moderate signs of aging, while Defyne works to smooth and plump deeper creases and folds. Both Restylane Refyne and Defyne are for patients 21 years of age or older, and the outcome typically lasts about one year, although your experience may vary. Some minor bruising, swelling, and redness is common, though these effects usually subside quickly. We also offer OcuMend to help minimize side effects. To learn more about Restylane, visit

What to Expect at Our Princeton, NJ Medical Spa

Dr. Eugenie Brunner, a top facial plastic surgeon in Princeton, NJ, will evaluate your areas of concerns and develop a customized treatment plan. If you’re anxious about needles, Dr. Brunner offers Pro-Nox™, a safe and convenient inhalant that you can breathe in to relieve discomfort throughout the procedure. She will then administer the dermal filler into a series of targeted locations to achieve the optimal outcome. Both Restylane Refyne and Defyne can provide instantaneous results, so you should be able to see the effects right away. Some bruising and tenderness may occur, which is why our medical spa uses the OcuMend adhesive patch to reduce these symptoms. There are more preventative measure you can take to reduce bruising – as can be found here. Once the procedure is complete, typically 15 to 30 minutes after beginning, you can return to your normal schedule.

OcuMend Healing Gel Patch

To reduce the unwanted effects of dermal filler injections, OcuMend can be used to minimize and potentially eliminate bruising and redness. Dr. Brunner offers this innovative treatment with all cosmetic injectable treatments to enhance your recovery and outcome.

Would you like to learn more about Restylane Refyne and Defyne? Talk to our skilled medical spa team today to schedule a consultation and discuss your goals with Dr. Brunner at our Princeton, NJ office.

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Double Board Certified: Facial Plastic & Reconstructive Surgery & Otolaryngology Head & Neck Surgery

Most Comprehensive Skin Rejuvenation Laser Center in Central New Jersey

Dr. Eugenie Brunner, winner of NJ Top Docs Award in 2020, Princeton, NJ.

Top Doctor 2020 - NJ TopDocs

Dr. Eugenie Brunner selected as New Jersey's top plastic surgeon in 2020

Select Surgeon's Top Plastic Surgeon in New Jersey for Laser Resurfacing and Tattoo Removal

Thousands of Cosmetic Facial Plastic Procedures Performed

Dr. Eugenie Brunner was awarded the Castle-Connolly Award

Castle Connolly - NEW YORK METRO AREA

Castle Connolly Top Doctor for more than 10 years (2009-2022) in Cosmetic Facial Plastic Surgery

Patients' Choice Award for Favorite Physician

2010, 2011, 2016-2020

Town Topics Readers' Choice Awards

2018, 2019, 2021

Fellow, American Academy of Facial Plastic & Reconstructive Surgery

Logo of Compassionate Doctor Award that Dr. Brunner received Princeton, NJ

Compassionate Doctor

Fellow, American College of Surgeons

Dr. Eugenie Brunner won the compassionate Dr. award in 2020, New Jersey.

Compassionate Doctor Award 2020

5.0 Stars from 22 Reviews

Vote Dr. Brunner for the Town Topics Reader's Choice Awards Best Plastic Surgeon.

Dr. Brunner won the past three years and would be honored if you would vote for her for Best Plastic Surgeon. You can vote once each day from August 3rd to September 28th, so please vote often if you can.

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